STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIX91267.1Metal-dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)    
Predicted Functional Partners:
mutY
Adenine glycosylase; Adenine glycosylase active on G-A mispairs.
       0.816
KIX90104.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.757
KIX91269.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0374 family.
       0.756
ytkD
Nucleoside triphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Nudix hydrolase family.
  
     0.736
secE
Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
  
   
 0.717
rsbW
Serine/threonine protein kinase; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
  
     0.688
sigB
RNA polymerase sigma factor SigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
     0.637
pcrB
Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond- formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.
  
     0.612
KIX91509.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.575
KIX90543.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.574
Your Current Organism:
Staphylococcus microti
NCBI taxonomy Id: 569857
Other names: CCM 4903, CCUG 55861, DSM 22147, NCTC 13832, S. microti, Staphylococcus microti Novakova et al. 2010, Staphylococcus sp. CCM 4903, Staphylococcus sp. CCM 4904, strain 4005-LJ(m)
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.