Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cas2_1CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (101 aa)    
Predicted Functional Partners:
cas1_1
CRISPR-associated protein Cas1; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.988
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 0.949
csm1
CRISPR-associated protein Csm1; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.900
csm3
CRISPR-associated protein Cmr4; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.880
csm5
CRISPR-associated protein Csm5; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.877
KIX91210.1
CRISPR-associated protein Csm4; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.868
KIX91213.1
CRISPR-associated protein Cas6; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.854
csm2
CRISPR-associated protein Csm2; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.847
csn
CRISPR-associated protein Cas9; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans- encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. [...]
 
   
 0.825
csm6
CRISPR-associated protein Csm6; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.780
Your Current Organism:
Staphylococcus microti
NCBI taxonomy Id: 569857
Other names: CCM 4903, CCUG 55861, DSM 22147, NCTC 13832, S. microti, Staphylococcus microti Novakova et al. 2010, Staphylococcus sp. CCM 4903, Staphylococcus sp. CCM 4904, strain 4005-LJ(m)
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