| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KIX91046.1 | lacA | TP70_04830 | TP70_04820 | PTS fructose transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Galactose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.774 |
| KIX91046.1 | lacB | TP70_04830 | TP70_04815 | PTS fructose transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Galactose-6-phosphate isomerase; Catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.817 |
| KIX91046.1 | lacC | TP70_04830 | TP70_04810 | PTS fructose transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tagatose-6-phosphate kinase; Catalyzes the formation of tagatose 1,6-bisphosphate from tagatose 6-phosphate and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | 0.504 |
| KIX91046.1 | lacD1 | TP70_04830 | TP70_04805 | PTS fructose transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tagatose-bisphosphate aldolase; Catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.819 |
| KIX91046.1 | lacE | TP70_04830 | TP70_07140 | PTS fructose transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS system lactose-specific transporter subunits IICB; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.525 |
| bglA | lacA | TP70_03565 | TP70_04820 | aryl-phospho-beta-D-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 1 family. | Galactose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.783 |
| bglA | lacB | TP70_03565 | TP70_04815 | aryl-phospho-beta-D-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 1 family. | Galactose-6-phosphate isomerase; Catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.783 |
| bglA | lacE | TP70_03565 | TP70_07140 | aryl-phospho-beta-D-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 1 family. | PTS system lactose-specific transporter subunits IICB; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.995 |
| fruK | lacA | TP70_01155 | TP70_04820 | Phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | Galactose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.787 |
| fruK | lacB | TP70_01155 | TP70_04815 | Phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | Galactose-6-phosphate isomerase; Catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.789 |
| fruK | lacD1 | TP70_01155 | TP70_04805 | Phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | Tagatose-bisphosphate aldolase; Catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.804 |
| fruK | lacE | TP70_01155 | TP70_07140 | Phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | PTS system lactose-specific transporter subunits IICB; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.920 |
| fruK | pfkA | TP70_01155 | TP70_10350 | Phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.881 |
| lacA | KIX91046.1 | TP70_04820 | TP70_04830 | Galactose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS fructose transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.774 |
| lacA | bglA | TP70_04820 | TP70_03565 | Galactose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | aryl-phospho-beta-D-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 1 family. | 0.783 |
| lacA | fruK | TP70_04820 | TP70_01155 | Galactose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | 0.787 |
| lacA | lacB | TP70_04820 | TP70_04815 | Galactose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Galactose-6-phosphate isomerase; Catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.989 |
| lacA | lacC | TP70_04820 | TP70_04810 | Galactose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tagatose-6-phosphate kinase; Catalyzes the formation of tagatose 1,6-bisphosphate from tagatose 6-phosphate and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | 0.993 |
| lacA | lacD1 | TP70_04820 | TP70_04805 | Galactose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tagatose-bisphosphate aldolase; Catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.933 |
| lacA | lacE | TP70_04820 | TP70_07140 | Galactose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS system lactose-specific transporter subunits IICB; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.832 |