Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KIX90765.1Rod shape-determining protein MreD; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)    
Predicted Functional Partners:
KIX90764.1
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
 
 0.996
ezrA
Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
   
 0.858
ftsL
Cell division protein FtsL; Essential cell division protein; Belongs to the FtsL family.
  
   
 0.788
KIX90767.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.756
KIX90624.1
Disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.747
KIX89777.1
5-bromo-4-chloroindolyl phosphate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.742
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
     
 0.734
gpsB
Cell division protein GpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
  
   
 0.726
rpmA
50S ribosomal protein L27; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL27 family.
     
 0.716
KIX91592.1
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.712
Your Current Organism:
Staphylococcus microti
NCBI taxonomy Id: 569857
Other names: CCM 4903, CCUG 55861, DSM 22147, NCTC 13832, S. microti, Staphylococcus microti Novakova et al. 2010, Staphylococcus sp. CCM 4903, Staphylococcus sp. CCM 4904, strain 4005-LJ(m)
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