Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (305 aa)    
Predicted Functional Partners:
lplJ
Lipoate--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.980
gcvH
Glycine cleavage system protein H; Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate; Belongs to the GcvH family.
 
 0.959
lipL
Lipoate--protein ligase; Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes; Belongs to the octanoyltransferase LipL family.
  
 
 0.922
lipM
Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation.
 
 
 0.895
nfuA
Nitrogen fixation protein NifU; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.890
yutD
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.842
yfkN_1
5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5'-nucleotidase family.
       0.746
yfcA_1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.733
KIX90633.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.728
hmrB
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
     
 0.584
Your Current Organism:
Staphylococcus microti
NCBI taxonomy Id: 569857
Other names: CCM 4903, CCUG 55861, DSM 22147, NCTC 13832, S. microti, Staphylococcus microti Novakova et al. 2010, Staphylococcus sp. CCM 4903, Staphylococcus sp. CCM 4904, strain 4005-LJ(m)
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