Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lacFPTS system lactose-specific transporter subunit IIA; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; Derived by automated computational analysis using gene prediction method: Protein Homology. (106 aa)    
Predicted Functional Partners:
lacE
PTS system lactose-specific transporter subunits IICB; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
lacG
6-phospho-beta-galactosidase; Catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 1 family.
 
 
 0.979
bglA
aryl-phospho-beta-D-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 1 family.
 
 
 0.953
ptsH
Phosphocarrier protein HPr; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.932
glcT_2
Transcription antiterminator lact; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.917
lacC
Tagatose-6-phosphate kinase; Catalyzes the formation of tagatose 1,6-bisphosphate from tagatose 6-phosphate and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.886
fruK
Phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.766
lacD1
Tagatose-bisphosphate aldolase; Catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.756
KIX91177.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.684
bglF
PTS beta-glucoside transporter subunit IIABC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.675
Your Current Organism:
Staphylococcus microti
NCBI taxonomy Id: 569857
Other names: CCM 4903, CCUG 55861, DSM 22147, NCTC 13832, S. microti, Staphylococcus microti Novakova et al. 2010, Staphylococcus sp. CCM 4903, Staphylococcus sp. CCM 4904, strain 4005-LJ(m)
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