Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KIX90343.1Response regulator SaeR; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)    
Predicted Functional Partners:
saeS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.980
KIX91752.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.975
phoR
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.941
ssrB
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.937
vicS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.898
graS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.872
arlS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.816
KIX90344.1
DoxX family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.812
ribA
GTP cyclohydrolase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.721
sigA
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.636
Your Current Organism:
Staphylococcus microti
NCBI taxonomy Id: 569857
Other names: CCM 4903, CCUG 55861, DSM 22147, NCTC 13832, S. microti, Staphylococcus microti Novakova et al. 2010, Staphylococcus sp. CCM 4903, Staphylococcus sp. CCM 4904, strain 4005-LJ(m)
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