Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
iolS_1Aldo/keto reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)    
Predicted Functional Partners:
iolC
Fructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.733
KIX90458.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.691
KIX91392.1
Phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.603
pdxK
Pyridoxal kinase; Catalyzes the phosphorylation of three vitamin B6 precursors, pyridoxal, pyridoxine and pyridoxamine; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.603
glpF
Glycerol transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 
 0.572
glcA_2
Glucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.571
nanK
N-acetylmannosamine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.541
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
  0.481
KIX90265.1
4-oxalomesaconate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.458
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
    
   0.434
Your Current Organism:
Staphylococcus microti
NCBI taxonomy Id: 569857
Other names: CCM 4903, CCUG 55861, DSM 22147, NCTC 13832, S. microti, Staphylococcus microti Novakova et al. 2010, Staphylococcus sp. CCM 4903, Staphylococcus sp. CCM 4904, strain 4005-LJ(m)
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