Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pxpALamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (253 aa)    
Predicted Functional Partners:
kipI_2
Allophanate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.995
KIX91693.1
Allophanate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.988
KIX90161.1
Iron transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.973
kipI_1
Allophanate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.961
accB_1
acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.873
accC_1
acetyl-CoA carboxylase biotin carboxylase subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.867
glnA
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.846
gluD
Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
  0.844
pruA
Catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.844
purQ
Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...]
     
  0.844
Your Current Organism:
Staphylococcus microti
NCBI taxonomy Id: 569857
Other names: CCM 4903, CCUG 55861, DSM 22147, NCTC 13832, S. microti, Staphylococcus microti Novakova et al. 2010, Staphylococcus sp. CCM 4903, Staphylococcus sp. CCM 4904, strain 4005-LJ(m)
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.