Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
iscS_2Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)    
Predicted Functional Partners:
thiI
Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
 0.994
uscU
Nitrogen fixation protein NifU; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.981
moeB_3
Molybdopterin biosynthesis protein MoeB; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.897
KIX90519.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sulfur carrier protein TusA family.
   
 0.886
iscS_1
Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.866
KIX90137.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.807
hmrB
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
 
 0.760
KIX90620.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family.
 
 
 0.695
nfuA
Nitrogen fixation protein NifU; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.675
siet
Signal peptide protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.670
Your Current Organism:
Staphylococcus microti
NCBI taxonomy Id: 569857
Other names: CCM 4903, CCUG 55861, DSM 22147, NCTC 13832, S. microti, Staphylococcus microti Novakova et al. 2010, Staphylococcus sp. CCM 4903, Staphylococcus sp. CCM 4904, strain 4005-LJ(m)
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