Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
phoRHistidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (569 aa)    
Predicted Functional Partners:
phoP
PhoP family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.997
KIX90343.1
Response regulator SaeR; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.941
vicR
PhoP family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.866
srrA
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.854
arlR
Response regulator ArlR; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.849
hssR
Heme transporter CcmC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.838
graR
Response regulator GraR; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.766
ribA
GTP cyclohydrolase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
  0.716
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
       0.637
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
       0.631
Your Current Organism:
Staphylococcus microti
NCBI taxonomy Id: 569857
Other names: CCM 4903, CCUG 55861, DSM 22147, NCTC 13832, S. microti, Staphylococcus microti Novakova et al. 2010, Staphylococcus sp. CCM 4903, Staphylococcus sp. CCM 4904, strain 4005-LJ(m)
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