Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
katACatalase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the catalase family. (498 aa)    
Predicted Functional Partners:
ahpC
Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
   
 
 0.775
sodA
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 0.739
bsaA
Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutathione peroxidase family.
  
 
 0.612
yhbO
General stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.603
hchA
Chaperone protein HchA; Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.603
hmp
Nitric oxide dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the globin family.
      
 0.577
ahpF
NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.575
lysP_2
Gamma-aminobutyrate permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.546
tal
Transaldolase; Similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.524
KIX91186.1
acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.518
Your Current Organism:
Staphylococcus microti
NCBI taxonomy Id: 569857
Other names: CCM 4903, CCUG 55861, DSM 22147, NCTC 13832, S. microti, Staphylococcus microti Novakova et al. 2010, Staphylococcus sp. CCM 4903, Staphylococcus sp. CCM 4904, strain 4005-LJ(m)
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