Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
msrA2Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (172 aa)    
Predicted Functional Partners:
msrB
Methionine sulfoxide reductase B; This stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.985
KIX90040.1
Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.778
trxA_1
Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.600
trxA_3
Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.600
KIX90299.1
Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.590
KIX89755.1
LytR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.529
bsaA
Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutathione peroxidase family.
   
 
 0.478
fmtC
Phosphatidylglycerol lysyltransferase; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
     
 0.434
Your Current Organism:
Staphylococcus microti
NCBI taxonomy Id: 569857
Other names: CCM 4903, CCUG 55861, DSM 22147, NCTC 13832, S. microti, Staphylococcus microti Novakova et al. 2010, Staphylococcus sp. CCM 4903, Staphylococcus sp. CCM 4904, strain 4005-LJ(m)
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