Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
arlRResponse regulator ArlR; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)    
Predicted Functional Partners:
arlS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.998
KIX91752.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.926
graS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.898
saeS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.852
phoR
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.849
ssrB
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.840
vicS
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.812
sucA
2-oxoglutarate dehydrogenase; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
     
 0.744
sucB
Dihydrolipoamide succinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.736
ribA
GTP cyclohydrolase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.721
Your Current Organism:
Staphylococcus microti
NCBI taxonomy Id: 569857
Other names: CCM 4903, CCUG 55861, DSM 22147, NCTC 13832, S. microti, Staphylococcus microti Novakova et al. 2010, Staphylococcus sp. CCM 4903, Staphylococcus sp. CCM 4904, strain 4005-LJ(m)
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