node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEO01843.1 | SEO01869.1 | SAMN04490248_10151 | SAMN04490248_10152 | Aspartate aminotransferase. | DNA-binding transcriptional regulator, Lrp family. | 0.709 |
SEO01843.1 | SEO01892.1 | SAMN04490248_10151 | SAMN04490248_10153 | Aspartate aminotransferase. | Lrp/AsnC family transcriptional regulator. | 0.709 |
SEO01843.1 | ilvC | SAMN04490248_10151 | SAMN04490248_10154 | Aspartate aminotransferase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.589 |
SEO01869.1 | SEO01843.1 | SAMN04490248_10152 | SAMN04490248_10151 | DNA-binding transcriptional regulator, Lrp family. | Aspartate aminotransferase. | 0.709 |
SEO01869.1 | SEO01892.1 | SAMN04490248_10152 | SAMN04490248_10153 | DNA-binding transcriptional regulator, Lrp family. | Lrp/AsnC family transcriptional regulator. | 0.877 |
SEO01869.1 | SEO16708.1 | SAMN04490248_10152 | SAMN04490248_10282 | DNA-binding transcriptional regulator, Lrp family. | Transcriptional regulator, AsnC family. | 0.736 |
SEO01869.1 | SEO92671.1 | SAMN04490248_10152 | SAMN04490248_11653 | DNA-binding transcriptional regulator, Lrp family. | DNA-binding transcriptional regulator, Lrp family. | 0.637 |
SEO01869.1 | SEP00649.1 | SAMN04490248_10152 | SAMN04490248_11937 | DNA-binding transcriptional regulator, Lrp family. | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.624 |
SEO01869.1 | ilvC | SAMN04490248_10152 | SAMN04490248_10154 | DNA-binding transcriptional regulator, Lrp family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.717 |
SEO01892.1 | SEO01843.1 | SAMN04490248_10153 | SAMN04490248_10151 | Lrp/AsnC family transcriptional regulator. | Aspartate aminotransferase. | 0.709 |
SEO01892.1 | SEO01869.1 | SAMN04490248_10153 | SAMN04490248_10152 | Lrp/AsnC family transcriptional regulator. | DNA-binding transcriptional regulator, Lrp family. | 0.877 |
SEO01892.1 | SEO16708.1 | SAMN04490248_10153 | SAMN04490248_10282 | Lrp/AsnC family transcriptional regulator. | Transcriptional regulator, AsnC family. | 0.750 |
SEO01892.1 | SEO92671.1 | SAMN04490248_10153 | SAMN04490248_11653 | Lrp/AsnC family transcriptional regulator. | DNA-binding transcriptional regulator, Lrp family. | 0.430 |
SEO01892.1 | SEP00649.1 | SAMN04490248_10153 | SAMN04490248_11937 | Lrp/AsnC family transcriptional regulator. | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.624 |
SEO01892.1 | ilvC | SAMN04490248_10153 | SAMN04490248_10154 | Lrp/AsnC family transcriptional regulator. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.717 |
SEO16708.1 | SEO01869.1 | SAMN04490248_10282 | SAMN04490248_10152 | Transcriptional regulator, AsnC family. | DNA-binding transcriptional regulator, Lrp family. | 0.736 |
SEO16708.1 | SEO01892.1 | SAMN04490248_10282 | SAMN04490248_10153 | Transcriptional regulator, AsnC family. | Lrp/AsnC family transcriptional regulator. | 0.750 |
SEO16708.1 | SEP00649.1 | SAMN04490248_10282 | SAMN04490248_11937 | Transcriptional regulator, AsnC family. | uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.624 |
SEO92671.1 | SEO01869.1 | SAMN04490248_11653 | SAMN04490248_10152 | DNA-binding transcriptional regulator, Lrp family. | DNA-binding transcriptional regulator, Lrp family. | 0.637 |
SEO92671.1 | SEO01892.1 | SAMN04490248_11653 | SAMN04490248_10153 | DNA-binding transcriptional regulator, Lrp family. | Lrp/AsnC family transcriptional regulator. | 0.430 |