STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEP14750.1(R)-ethylmalonyl-CoA mutase. (659 aa)    
Predicted Functional Partners:
SEP01324.1
methylmalonyl-CoA mutase.
 
0.999
SEO03897.1
LAO/AO transport system kinase.
  
 0.997
SEO56678.1
methylmalonyl-CoA epimerase /ethylmalonyl-CoA epimerase.
 
  
 0.982
SEP14784.1
crotonyl-CoA carboxylase/reductase.
  
 0.961
SEP07709.1
Acetyl-CoA hydrolase/transferase C-terminal domain-containing protein.
  
 
 0.943
SEO64635.1
Indolepyruvate ferredoxin oxidoreductase.
    
 0.906
SEO95600.1
Indolepyruvate ferredoxin oxidoreductase.
    
 0.906
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.896
SEP15320.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
    
 0.891
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.890
Your Current Organism:
Salinihabitans flavidus
NCBI taxonomy Id: 569882
Other names: CCUG 56758, DSM 27842, KCTC 22485, Rhodobacteraceae bacterium ISL-46, S. flavidus, Salinihabitans flavidus Yoon et al. 2009, strain ISL-46
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