STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phhAPhenylalanine 4-hydroxylase; phenylalanine 4-hydroxylase; catalyzes the formation of 4a-hydroxytetrahydrobiopterin and tyrosine from phenylalanine and tetrahydrobiopterin; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)    
Predicted Functional Partners:
KPM83233.1
Pterin-4-alpha-carbinolamine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
KPM83327.1
Aromatic amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.963
KPM83332.1
Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.945
KPM84360.1
Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.925
KPM85580.1
Diacylglycerol kinase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
     
 0.917
KPM85023.1
4-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.915
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
 
  
 0.890
tyrA
Chorismate mutase; Catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.843
KPM84525.1
Maleylacetoacetate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.784
KPM83235.1
Methionine gamma-lyase; Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.738
Your Current Organism:
Pseudoalteromonas lipolytica
NCBI taxonomy Id: 570156
Other names: CGMCC 1.8499, JCM 15903, P. lipolytica, Pseudoalteromonas lipolytica Xu et al. 2010, Pseudoalteromonas sp. ASS5B, Pseudoalteromonas sp. ASW16, strain LMEB 39
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