STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHG47517.13-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. (438 aa)    
Predicted Functional Partners:
SHG49589.1
Mevalonate kinase.
 
 0.972
SHG47536.1
Mevalonate kinase.
 
 0.970
SHG97677.1
acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
 
  
 0.917
SHG22839.1
acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
 
  
 0.906
SHG49619.1
Diphosphomevalonate decarboxylase.
 
 
 0.903
menA
1,4-dihydroxy-2-naphthoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
    
 
 0.845
kmo
Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
   
  
 0.717
SHG47486.1
Dipeptidyl-peptidase-4.
       0.538
SHG47464.1
Proton-dependent oligopeptide transporter, POT family.
       0.519
SHG30824.1
ATPase family associated with various cellular activities (AAA).
    
 
 0.483
Your Current Organism:
Flagellimonas flava
NCBI taxonomy Id: 570519
Other names: DSM 22638, F. flava, Flavobacteriaceae bacterium A11, KCTC 22665, Spongiibacterium flavum, Spongiibacterium flavum Yoon et al. 2012, strain A11
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.