STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHG73756.1Ion channel. (220 aa)    
Predicted Functional Partners:
SHG89873.1
Predicted ATPase.
  
 
 0.842
SHG73694.1
Outer membrane protein TolC.
 
     0.823
SHG73714.1
RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
     0.793
SHG73776.1
Hypothetical protein.
       0.773
SHG73737.1
Multidrug efflux pump subunit AcrB; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
     0.761
SHH09391.1
Putative membrane protein.
  
     0.641
SHG53018.1
Calcineurin-like phosphoesterase.
  
  
  0.552
SHG33027.1
Topoisomerase-4 subunit B.
    
 
 0.526
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.526
SHG54098.1
Putative membrane protein.
  
     0.499
Your Current Organism:
Flagellimonas flava
NCBI taxonomy Id: 570519
Other names: DSM 22638, F. flava, Flavobacteriaceae bacterium A11, KCTC 22665, Spongiibacterium flavum, Spongiibacterium flavum Yoon et al. 2012, strain A11
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