STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHG77960.1uroporphyrinogen-III synthase. (221 aa)    
Predicted Functional Partners:
SHG77939.1
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 0.999
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.978
SHG78097.1
Porphobilinogen synthase; Belongs to the ALAD family.
  
 0.935
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.887
SHG83968.1
uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
  
 
 0.878
SHG78031.1
Hypothetical protein; Manually curated.
 
     0.877
SHG50769.1
uroporphyrinogen-III synthase.
  
  
 
0.858
SHG78050.1
Coproporphyrinogen oxidase.
     
 0.804
SHG77897.1
Hypothetical protein.
       0.773
SHG78006.1
Ribosomal-protein-alanine N-acetyltransferase.
       0.746
Your Current Organism:
Flagellimonas flava
NCBI taxonomy Id: 570519
Other names: DSM 22638, F. flava, Flavobacteriaceae bacterium A11, KCTC 22665, Spongiibacterium flavum, Spongiibacterium flavum Yoon et al. 2012, strain A11
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