SHG95897.1 protein (Flagellimonas flava) - STRING interaction network

Nodes:

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

SHG95897.1

Protein of unknown function. (244 aa)

Predicted Functional Partners:

SHG95868.1

0.955

SHG95936.1

0.955

SHG95919.1

0.953

SHG95819.1

0.952

SHG95958.1

0.913

SHG95841.1

0.834

SHG95987.1

0.612

SHG24088.1

0.422

SHG35262.1

0.421

Your Current Organism:

Flagellimonas flava

NCBI taxonomy Id: 570519
Other names: DSM 22638, F. flava, Flavobacteriaceae bacterium A11, KCTC 22665, Spongiibacterium flavum, Spongiibacterium flavum Yoon et al. 2012, strain A11

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SHG24088.1	SHG95897.1	SAMN04488116_0487	SAMN04488116_3030	Type IV pili methyl-accepting chemotaxis transducer N-term.	Protein of unknown function.	0.422
SHG35262.1	SHG95868.1	SAMN04488116_1111	SAMN04488116_3029	Sugar phosphate isomerase/epimerase.	Protein of unknown function.	0.426
SHG35262.1	SHG95897.1	SAMN04488116_1111	SAMN04488116_3030	Sugar phosphate isomerase/epimerase.	Protein of unknown function.	0.421
SHG95819.1	SHG95841.1	SAMN04488116_3027	SAMN04488116_3028	Uncharacterized conserved protein, DUF58 family, contains vWF domain.	MoxR-like ATPase.	0.905
SHG95819.1	SHG95868.1	SAMN04488116_3027	SAMN04488116_3029	Uncharacterized conserved protein, DUF58 family, contains vWF domain.	Protein of unknown function.	0.953
SHG95819.1	SHG95897.1	SAMN04488116_3027	SAMN04488116_3030	Uncharacterized conserved protein, DUF58 family, contains vWF domain.	Protein of unknown function.	0.952
SHG95819.1	SHG95919.1	SAMN04488116_3027	SAMN04488116_3031	Uncharacterized conserved protein, DUF58 family, contains vWF domain.	Hypothetical protein.	0.941
SHG95819.1	SHG95936.1	SAMN04488116_3027	SAMN04488116_3032	Uncharacterized conserved protein, DUF58 family, contains vWF domain.	Uncharacterized membrane protein SpoIIM, required for sporulation.	0.955
SHG95819.1	SHG95958.1	SAMN04488116_3027	SAMN04488116_3033	Uncharacterized conserved protein, DUF58 family, contains vWF domain.	Uncharacterized membrane protein YckC, RDD family.	0.908
SHG95819.1	SHG95987.1	SAMN04488116_3027	SAMN04488116_3034	Uncharacterized conserved protein, DUF58 family, contains vWF domain.	Uncharacterized membrane protein YeiH.	0.564
SHG95841.1	SHG95819.1	SAMN04488116_3028	SAMN04488116_3027	MoxR-like ATPase.	Uncharacterized conserved protein, DUF58 family, contains vWF domain.	0.905
SHG95841.1	SHG95868.1	SAMN04488116_3028	SAMN04488116_3029	MoxR-like ATPase.	Protein of unknown function.	0.826
SHG95841.1	SHG95897.1	SAMN04488116_3028	SAMN04488116_3030	MoxR-like ATPase.	Protein of unknown function.	0.834
SHG95841.1	SHG95919.1	SAMN04488116_3028	SAMN04488116_3031	MoxR-like ATPase.	Hypothetical protein.	0.787
SHG95841.1	SHG95936.1	SAMN04488116_3028	SAMN04488116_3032	MoxR-like ATPase.	Uncharacterized membrane protein SpoIIM, required for sporulation.	0.846
SHG95841.1	SHG95958.1	SAMN04488116_3028	SAMN04488116_3033	MoxR-like ATPase.	Uncharacterized membrane protein YckC, RDD family.	0.703
SHG95841.1	SHG95987.1	SAMN04488116_3028	SAMN04488116_3034	MoxR-like ATPase.	Uncharacterized membrane protein YeiH.	0.567
SHG95868.1	SHG35262.1	SAMN04488116_3029	SAMN04488116_1111	Protein of unknown function.	Sugar phosphate isomerase/epimerase.	0.426
SHG95868.1	SHG95819.1	SAMN04488116_3029	SAMN04488116_3027	Protein of unknown function.	Uncharacterized conserved protein, DUF58 family, contains vWF domain.	0.953
SHG95868.1	SHG95841.1	SAMN04488116_3029	SAMN04488116_3028	Protein of unknown function.	MoxR-like ATPase.	0.826

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Network Stats

number of nodes:

11

number of edges:

53

average node degree:

9.64

avg. local clustering coefficient:

0.962

expected number of edges:

11

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:1902600

Proton transmembrane transport

4 of 26

1.73

1.4

0.0011

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004129

Cytochrome-c oxidase activity

3 of 5

2.32

1.9

0.00025

GO:0015453

Oxidoreduction-driven active transmembrane transporter activity

4 of 22

1.8

1.73

0.00020

GO:0015078

Proton transmembrane transporter activity

4 of 28

1.7

1.63

0.00025

GO:0009055

Electron transfer activity

5 of 49

1.55

1.58

0.00015

GO:0022853

Active ion transmembrane transporter activity

4 of 32

1.64

1.58

0.00026

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016021

Integral component of membrane

11 of 819

0.67

0.63

6.13e-06

GO:0005886

Plasma membrane

8 of 616

0.66

0.52

0.0017

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2400

Oxidative phosphorylation, and SLBB domain

10 of 42

1.92

5.35

3.99e-16

CL:2453

Mixed, incl. Respiratory chain, and Peptidase M16 inactive domain

6 of 12

2.24

4.46

4.02e-10

CL:2396

Mixed, incl. Oxidative phosphorylation, and Heme binding

11 of 77

1.7

4.27

3.99e-16

CL:2457

Respiratory chain, and Rieske [2Fe-2S] domain

5 of 7

2.4

4.06

8.85e-09

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00190

Oxidative phosphorylation

9 of 64

1.69

3.71

1.21e-12

map01100

Metabolic pathways

10 of 1522

0.36

0.26

0.0406

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0070469

Respirasome

3 of 30

1.54

0.89

0.0134

GOCC:0031975

Envelope

4 of 116

1.08

0.62

0.0247

GOCC:0016020

Membrane

9 of 721

0.64

0.48

0.0034

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0249

Electron transport

3 of 12

1.94

1.51

0.00096

KW-0186

Copper

2 of 2

2.54

1.48

0.0019

KW-0350

Heme biosynthesis

2 of 3

2.37

1.39

0.0026

KW-0679

Respiratory chain

2 of 6

2.07

1.16

0.0062

KW-1133

Transmembrane helix

9 of 648

0.69

0.55

0.00096

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