STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
minCSeptum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (228 aa)    
Predicted Functional Partners:
SIS36653.1
Septum site-determining protein MinD.
 
 
 0.999
SIS36649.1
Rod shape-determining protein MreD.
 
  
 0.947
SIS36647.1
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
  
 0.942
SIS36645.1
Rod shape-determining protein MreB.
  
  
 0.829
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
   
 
 0.808
SIS64874.1
GIY-YIG catalytic domain-containing protein.
   
 
 0.777
SIS43132.1
PDZ domain-containing protein.
  
   
 0.707
SIS36657.1
Hypothetical protein.
 
     0.576
ffh
Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
  
 0.544
SIS37587.1
Flagellar biosynthesis protein FlhG.
  
   
 0.513
Your Current Organism:
Salimicrobium flavidum
NCBI taxonomy Id: 570947
Other names: CCUG 56755, DSM 23127, KCTC 13260, S. flavidum, Salimicrobium flavidum Yoon et al. 2009, Salimicrobium sp. ISL-25, strain ISL-25
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