node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SIS37760.1 | SIS40844.1 | SAMN05421687_101443 | SAMN05421687_102265 | [Acyl-carrier-protein] S-malonyltransferase. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.497 |
SIS37760.1 | guaA | SAMN05421687_101443 | SAMN05421687_11036 | [Acyl-carrier-protein] S-malonyltransferase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.421 |
SIS37760.1 | hemL | SAMN05421687_101443 | SAMN05421687_1067 | [Acyl-carrier-protein] S-malonyltransferase. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.710 |
SIS37760.1 | hemL-2 | SAMN05421687_101443 | SAMN05421687_10722 | [Acyl-carrier-protein] S-malonyltransferase. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.751 |
SIS40844.1 | SIS37760.1 | SAMN05421687_102265 | SAMN05421687_101443 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | [Acyl-carrier-protein] S-malonyltransferase. | 0.497 |
SIS40844.1 | SIS50818.1 | SAMN05421687_102265 | SAMN05421687_10723 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.506 |
SIS40844.1 | SIS50830.1 | SAMN05421687_102265 | SAMN05421687_10724 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.424 |
SIS40844.1 | guaA | SAMN05421687_102265 | SAMN05421687_11036 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.512 |
SIS40844.1 | hemL | SAMN05421687_102265 | SAMN05421687_1067 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.489 |
SIS40844.1 | hemL-2 | SAMN05421687_102265 | SAMN05421687_10722 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.489 |
SIS50818.1 | SIS40844.1 | SAMN05421687_10723 | SAMN05421687_102265 | Porphobilinogen synthase; Belongs to the ALAD family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.506 |
SIS50818.1 | SIS50830.1 | SAMN05421687_10723 | SAMN05421687_10724 | Porphobilinogen synthase; Belongs to the ALAD family. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.993 |
SIS50818.1 | SIS50854.1 | SAMN05421687_10723 | SAMN05421687_10726 | Porphobilinogen synthase; Belongs to the ALAD family. | HemX protein. | 0.835 |
SIS50818.1 | hemA | SAMN05421687_10723 | SAMN05421687_10727 | Porphobilinogen synthase; Belongs to the ALAD family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.954 |
SIS50818.1 | hemC | SAMN05421687_10723 | SAMN05421687_10725 | Porphobilinogen synthase; Belongs to the ALAD family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.998 |
SIS50818.1 | hemL | SAMN05421687_10723 | SAMN05421687_1067 | Porphobilinogen synthase; Belongs to the ALAD family. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.984 |
SIS50818.1 | hemL-2 | SAMN05421687_10723 | SAMN05421687_10722 | Porphobilinogen synthase; Belongs to the ALAD family. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.995 |
SIS50830.1 | SIS40844.1 | SAMN05421687_10724 | SAMN05421687_102265 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.424 |
SIS50830.1 | SIS50818.1 | SAMN05421687_10724 | SAMN05421687_10723 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen synthase; Belongs to the ALAD family. | 0.993 |
SIS50830.1 | SIS50854.1 | SAMN05421687_10724 | SAMN05421687_10726 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | HemX protein. | 0.930 |