Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKL33396.1Sorbitol-6-phosphate 2-dehydrogenase; Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (267 aa)    
Predicted Functional Partners:
srlA
PTS system glucitol/sorbitol-specific transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates along with their translocation across the cell membrane; the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.975
AKL34921.1
PTS sorbitol transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.974
srlE
PTS system glucitol/sorbitol-specific transporter subunit IIB; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; subunit IIB transfers the phosphoryl group to the substrate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.973
AKL34919.1
PTS sorbitol transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.972
AKL34831.1
PTS system glucitol/sorbitol-specific transporter subunit IIA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.971
AKL33401.1
L-sorbose 1-phosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.960
mtlD
Mannitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.941
AKL34920.1
PTS sorbitol transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.940
srlD
Sorbitol-6-phosphate 2-dehydrogenase; Catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 
0.924
pfkA_1-2
Permease; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family.
  
 
  0.915
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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