Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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[Homology]
Score
AKL33540.1Among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)    
Predicted Functional Partners:
smf
DNA processing protein DprA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.887
AKL33959.1
Required for utilization of DNA as the sole source of carbon and energy; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.875
AKL34254.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0102 family.
 
  
 0.692
ruvC
Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
 
   
 0.676
AKL37787.1
Competence protein ComEA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.583
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
  
   
 0.572
recA
Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
 
  
 0.560
AKL37219.1
Competence protein ComEC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.558
AKL35919.1
Clp protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.509
hofQ
Porin; Outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.504
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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