Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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fieFFerrous iron transporter; Cation-efflux transporter that may have a role in detoxification. (298 aa)    
Predicted Functional Partners:
frmR
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.606
copA
Copper-transporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.596
zntA
Zinc ABC transporter ATPase; P-type ATPase involved in the export of lead, cadmium, zinc and mercury; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.589
arsC-2
Arsenate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.583
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
    0.579
ldh
Lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
    0.579
gdx
Multidrug transporter; Guanidinium ion exporter. Couples guanidinium export to the proton motive force, exchanging one guanidinium ion for two protons. Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Gdx/SugE subfamily.
      
 0.560
crcB
Camphor resistance protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
     
 0.556
cpxP
Periplasmic repressor CpxP; Repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.529
cpxA
Two-component sensor protein; Part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.518
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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