STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rhaBRhamnulokinase; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1- hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate. Belongs to the rhamnulokinase family. (488 aa)    
Predicted Functional Partners:
rhaA
Sugar isomerase; Catalyzes the formation of L-rhamnulose from L-rhamnose; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
rhaD
Rhamnulose-1-phosphate aldolase; Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. Belongs to the aldolase class II family. RhaD subfamily.
 
 
 0.992
rhaM
L-rhamnose mutarotase; Involved in the anomeric conversion of L-rhamnose.
 
  
 0.957
AKL36205.1
Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FGGY kinase family.
  
  
  0.917
AKL33872.1
Xylulose kinase; Catalyzes the formation of L-xylulose 5-phosphate and 3-dehydro-L-gulonate 6-phosphate from L-xylulose or 3-dehydro-L-gulonate, respectively; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.915
rhaR_3
Transcriptional regulator; Activates expression of the rhaSR operon in response to L- rhamnose.
 
  
 0.775
fucI
Sugar isomerase; Converts the aldose L-fucose into the corresponding ketose L- fuculose.
 
  
 0.757
rhaT
Rhamnose:proton symporter; Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
 
  
 0.652
fucU
Hypothetical protein; Involved in the anomeric conversion of L-fucose.
 
  
 0.635
rhaS
AraC family transcriptional regulator; Activates expression of the rhaBAD and rhaT operons.
 
  
 0.579
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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