STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lacYGalactoside permease; Lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; Derived by automated computational analysis using gene prediction method: Protein Homology. (421 aa)    
Predicted Functional Partners:
lacA
Galactoside O-acetyltransferase; Transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.848
AKL33609.1
Alpha-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.737
ebgA
beta-D-galactosidase; In Escherichia coli this is the second beta-galactosidase system; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.721
lacZ
beta-D-galactosidase; Forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 2 family.
 
  
 0.694
crr_1
PTS system glucose-specific transporter subunit IIA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.620
recF
Recombination protein F; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.
      
 0.588
AKL38142.1
alpha-N-arabinofuranosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 43 family.
 
  
 0.584
AKL37938.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.558
celB
Oligo-beta-mannoside permease IIC protein; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
      
 0.549
tynA
Tyramine oxidase; Catalyzes the formation of phenylacetaldehyde from 2-phenylethylamine; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.546
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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