Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKL33683.1Pectate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (723 aa)    
Predicted Functional Partners:
AKL34614.1
Oligogalacturonate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.956
AKL34607.1
Oligogalacturonate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.949
AKL37023.1
Pectate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.929
pemB
acyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.926
AKL37371.1
acyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.910
AKL37668.1
exo-poly-alpha-D-galacturonosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 28 family.
   
 0.638
manA
Mannose-6-phosphate isomerase; Catalyzes the formation of of fructose 6-phosphate from mannose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannose-6-phosphate isomerase type 1 family.
 
  
 0.540
ebgA
beta-D-galactosidase; In Escherichia coli this is the second beta-galactosidase system; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.435
glmU
Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
       0.402
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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