Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKL38734.1Adenine permease PurP; Involved in the transport or adenine; Derived by automated computational analysis using gene prediction method: Protein Homology. (446 aa)    
Predicted Functional Partners:
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.790
AKL33695.1
6-phosphogluconate phosphatase; YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.678
yjcD_2
Permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
0.626
uraA
Uracil transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.596
AKL35772.1
Permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.593
yicE
Xanthine permease XanP; High-affinity transporter for xanthine; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.578
xanP
Xanthine permease XanP; High-affinity transporter for xanthine; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.561
AKL36996.1
Pyrimidine permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.491
purE
N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
    0.477
purD
Phosphoribosylamine--glycine ligase; Catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family.
  
  
 0.474
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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