STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uhpTSugar phosphate antiporter; Cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (463 aa)    
Predicted Functional Partners:
AKL33743.1
Histidine kinase; Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.907
uhpA
Response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.821
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
      
 0.756
cyaA
Adenylate cyclase; Catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the adenylyl cyclase class-1 family.
      
 0.623
AKL33744.1
Regulatory protein UhpC; Membrane protein regulates uhpT expression; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
0.620
pitA
Phosphate transporter PitA; Involved in the transport of inorganic phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.584
uhpA_2
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.545
AKL33746.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.514
glpA
Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.478
glpQ
Glycerophosphodiester phosphodiesterase; Hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.445
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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