Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
bcsACellulose synthase; Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose. (873 aa)    
Predicted Functional Partners:
AKL33930.1
Cellulose synthase; Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family.
 
 0.998
AKL33927.1
Cell division protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.983
AKL33918.1
Cellulose synthase; Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); Belongs to the AcsB/BcsB family.
 
 0.982
AKL33922.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.982
AKL35444.1
UTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.921
AKL35820.1
Together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.921
otsA
Trehalose-6-phosphate synthase; Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family.
  
 
 0.914
bcsE
Required for cellulose biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.903
bcsZ
endo-1,4-D-glucanase; Catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.870
yhjQ
Chromosome partitioning protein ParA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.861
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
Server load: medium (58%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.