STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fucO_1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)    
Predicted Functional Partners:
AKL38379.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.892
AKL33783.1
Zinc-binding dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.680
AKL34661.1
Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.568
AKL35145.1
Aldehyde dehydrogenase; Ethanolamine utilization protein; catalyzes the formation of acetyl-CoA from acetaldehyde; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.558
AKL33946.1
Glutathione S-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.536
frmA
Catalyzes the formation of S-formylglutathione from S-(hydroxymethyl)glutathione; also catalyzes the formation of aldehyde or ketone from alcohols; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
   
 
 0.508
nifJ
Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.501
glgA
Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose.
   
    0.497
adhP
Ethanol-active dehydrogenase/acetaldehyde-active reductase; Similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.462
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
   
  
 0.438
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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