| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKL33968.1 | pitA | AB185_08685 | AB185_08680 | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphate transporter PitA; Involved in the transport of inorganic phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.634 |
| cysG | cysG-2 | AB185_09190 | AB185_12870 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.987 |
| cysG | pitA | AB185_09190 | AB185_08680 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Phosphate transporter PitA; Involved in the transport of inorganic phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.626 |
| cysG-2 | cysG | AB185_12870 | AB185_09190 | Sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.987 |
| cysG-2 | pitA | AB185_12870 | AB185_08680 | Sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | Phosphate transporter PitA; Involved in the transport of inorganic phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.626 |
| murA | pitA | AB185_10035 | AB185_08680 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | Phosphate transporter PitA; Involved in the transport of inorganic phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.767 |
| murA | uhpT | AB185_10035 | AB185_07490 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | Sugar phosphate antiporter; Cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.756 |
| phoR | phoU | AB185_29815 | AB185_07175 | Phosphate regulon sensor protein; Membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | 0.851 |
| phoR | pitA | AB185_29815 | AB185_08680 | Phosphate regulon sensor protein; Membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphate transporter PitA; Involved in the transport of inorganic phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.728 |
| phoR | ppa_1 | AB185_29815 | AB185_22320 | Phosphate regulon sensor protein; Membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Potassium ABC transporter ATPase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. | 0.501 |
| phoR | ppa_2 | AB185_29815 | AB185_33470 | Phosphate regulon sensor protein; Membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. | 0.545 |
| phoR | ppx | AB185_29815 | AB185_14900 | Phosphate regulon sensor protein; Membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; Derived by automated computational analysis using gene prediction method: Protein Homology. | Exopolyphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GppA/Ppx family. | 0.582 |
| phoU | phoR | AB185_07175 | AB185_29815 | Transcriptional regulator PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | Phosphate regulon sensor protein; Membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.851 |
| phoU | pitA | AB185_07175 | AB185_08680 | Transcriptional regulator PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | Phosphate transporter PitA; Involved in the transport of inorganic phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.633 |
| phoU | ppx | AB185_07175 | AB185_14900 | Transcriptional regulator PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | Exopolyphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GppA/Ppx family. | 0.452 |
| pitA | AKL33968.1 | AB185_08680 | AB185_08685 | Phosphate transporter PitA; Involved in the transport of inorganic phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.634 |
| pitA | cysG | AB185_08680 | AB185_09190 | Phosphate transporter PitA; Involved in the transport of inorganic phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.626 |
| pitA | cysG-2 | AB185_08680 | AB185_12870 | Phosphate transporter PitA; Involved in the transport of inorganic phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.626 |
| pitA | murA | AB185_08680 | AB185_10035 | Phosphate transporter PitA; Involved in the transport of inorganic phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.767 |
| pitA | phoR | AB185_08680 | AB185_29815 | Phosphate transporter PitA; Involved in the transport of inorganic phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphate regulon sensor protein; Membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.728 |
