Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nikCNickel transporter permease NikC; With NikABDE is involved in nickel transport into the cell; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)    
Predicted Functional Partners:
nikE
Nickel ABC transporter ATP-binding protein; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.
 
 0.999
nikD
Nickel ABC transporter ATP-binding protein; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.
 0.999
AKL33981.1
Nickel transporter permease NikB; With NikACDE is involved in nickel transport into the cell; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
AKL33982.1
Nickel ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
AKL35432.1
Methionine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.
 
 0.897
AKL35953.1
Peptide ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.
 
 0.895
dppD-2
DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.892
dppD
DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.891
nikR
Nickel responsive regulator; Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel.
  
  
 0.888
gsiA_20
Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.888
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
Server load: low (10%) [HD]