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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kefBPotassium transporter KefB; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. (601 aa)    
Predicted Functional Partners:
ywrO_1
Potassium transporter KefG; Required for KefB activity; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.975
kefF_2
Potassium transporter KefF; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC; Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.
 
 
 0.861
ywrO_1-2
MdaB protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.848
AKL34083.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.798
cvrA
Potassium/proton antiporter; K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
     
 0.790
AKL38372.1
NAD(P)H dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.741
mdaB
NADPH quinone reductase MdaB; Involved in drug resistance; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.730
hflB
ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
  
 0.718
AKL38135.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.681
AKL38649.1
NAD(P)H dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.680
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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