STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aaeB_2P-hydroxybenzoic acid efflux subunit AaeB; Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell; Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family. (655 aa)    
Predicted Functional Partners:
aaeA
P-hydroxybenzoic acid efflux subunit AaeA; Forms an efflux pump with AaeB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  
 0.975
aaeX
Transporter; Membrane protein AaeX; the gene is a member of the aaeXAB operon; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.954
AKL33809.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.746
yciC
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.744
ompX
Membrane protein; OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.738
AKL34866.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.721
AKL35678.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.720
yhcO
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.709
tus
DNA replication terminus site-binding protein; Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence; Belongs to the Tus family.
  
     0.702
nlpB
Lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
     0.698
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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