| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKL35021.1 | hpf | AB185_14450 | AB185_09965 | Signal peptidase I; Catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. | Ribosome hibernation promoting factor HPF; During stationary phase, promotes and stabilizes dimerization of 70S ribosomes by the ribosome modulation factor (RMF), leading to the formation of inactive 100S ribosomes. Belongs to the HPF/YfiA ribosome-associated protein family. Short HPF subfamily. | 0.478 |
| AKL35021.1 | ptsN | AB185_14450 | AB185_09960 | Signal peptidase I; Catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. | PTS system nitrogen regulatory protein IIA(Ntr); Seems to have a role in regulating nitrogen assimilation. | 0.561 |
| AKL35021.1 | rpoA | AB185_14450 | AB185_09510 | Signal peptidase I; Catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.759 |
| AKL35021.1 | rpoB | AB185_14450 | AB185_05790 | Signal peptidase I; Catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.458 |
| AKL35021.1 | rpoN | AB185_14450 | AB185_09970 | Signal peptidase I; Catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. | RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the nitrogen fixation genes. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein NifA for the expression of the nitrogen fixation proteins. | 0.898 |
| AKL35031.1 | rpoN | AB185_14510 | AB185_09970 | Histidine kinase; Part of the GlrKR two-component signal transduction system involved in the regulation of glmY; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the nitrogen fixation genes. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein NifA for the expression of the nitrogen fixation proteins. | 0.904 |
| AKL35031.1 | yfhA | AB185_14510 | AB185_14520 | Histidine kinase; Part of the GlrKR two-component signal transduction system involved in the regulation of glmY; Derived by automated computational analysis using gene prediction method: Protein Homology. | Response regulator GlrR; Probable member of a two-component regulatory system YfhA/YfhK. | 0.995 |
| glnG | rpoN | AB185_06945 | AB185_09970 | Nitrogen regulation protein NR(I); Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. | RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the nitrogen fixation genes. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein NifA for the expression of the nitrogen fixation proteins. | 0.920 |
| hpf | AKL35021.1 | AB185_09965 | AB185_14450 | Ribosome hibernation promoting factor HPF; During stationary phase, promotes and stabilizes dimerization of 70S ribosomes by the ribosome modulation factor (RMF), leading to the formation of inactive 100S ribosomes. Belongs to the HPF/YfiA ribosome-associated protein family. Short HPF subfamily. | Signal peptidase I; Catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. | 0.478 |
| hpf | ptsN | AB185_09965 | AB185_09960 | Ribosome hibernation promoting factor HPF; During stationary phase, promotes and stabilizes dimerization of 70S ribosomes by the ribosome modulation factor (RMF), leading to the formation of inactive 100S ribosomes. Belongs to the HPF/YfiA ribosome-associated protein family. Short HPF subfamily. | PTS system nitrogen regulatory protein IIA(Ntr); Seems to have a role in regulating nitrogen assimilation. | 0.878 |
| hpf | rpoN | AB185_09965 | AB185_09970 | Ribosome hibernation promoting factor HPF; During stationary phase, promotes and stabilizes dimerization of 70S ribosomes by the ribosome modulation factor (RMF), leading to the formation of inactive 100S ribosomes. Belongs to the HPF/YfiA ribosome-associated protein family. Short HPF subfamily. | RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the nitrogen fixation genes. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein NifA for the expression of the nitrogen fixation proteins. | 0.878 |
| nifA | rpoN | AB185_16955 | AB185_09970 | ATPase AAA; Required for activation of most nif operons, which are directly involved in nitrogen fixation. | RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the nitrogen fixation genes. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein NifA for the expression of the nitrogen fixation proteins. | 0.871 |
| pspF | rpoA | AB185_23660 | AB185_09510 | Phage shock protein; Transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.595 |
| pspF | rpoB | AB185_23660 | AB185_05790 | Phage shock protein; Transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.595 |
| pspF | rpoN | AB185_23660 | AB185_09970 | Phage shock protein; Transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the nitrogen fixation genes. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein NifA for the expression of the nitrogen fixation proteins. | 0.873 |
| ptsN | AKL35021.1 | AB185_09960 | AB185_14450 | PTS system nitrogen regulatory protein IIA(Ntr); Seems to have a role in regulating nitrogen assimilation. | Signal peptidase I; Catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. | 0.561 |
| ptsN | hpf | AB185_09960 | AB185_09965 | PTS system nitrogen regulatory protein IIA(Ntr); Seems to have a role in regulating nitrogen assimilation. | Ribosome hibernation promoting factor HPF; During stationary phase, promotes and stabilizes dimerization of 70S ribosomes by the ribosome modulation factor (RMF), leading to the formation of inactive 100S ribosomes. Belongs to the HPF/YfiA ribosome-associated protein family. Short HPF subfamily. | 0.878 |
| ptsN | rpoN | AB185_09960 | AB185_09970 | PTS system nitrogen regulatory protein IIA(Ntr); Seems to have a role in regulating nitrogen assimilation. | RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the nitrogen fixation genes. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein NifA for the expression of the nitrogen fixation proteins. | 0.914 |
| rpoA | AKL35021.1 | AB185_09510 | AB185_14450 | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Signal peptidase I; Catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family. | 0.759 |
| rpoA | pspF | AB185_09510 | AB185_23660 | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Phage shock protein; Transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.595 |