Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
manX_2PTS system N-acetylgalactosamine-specific transporter subunit IIB; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)    
Predicted Functional Partners:
manZ_1
PTS system N-acetylgalactosamine-specific transporter subunit IID; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IID with IIC forms the translocation channel; involved in N-acetylgalactosamine transport; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.997
agaC_1
PTS system N-acetylgalactosamine-specific transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.997
manX_1
PTS N-acetylgalactosamine transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.996
nagA-2
N-acetylglucosamine-6-phosphate deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.977
ptsH
PTS sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.920
kbaZ
Tagatose-bisphosphate aldolase; Component of the tagatose-1,6-bisphosphate aldolase KbaYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of KbaY. When expressed alone, KbaZ does not show any aldolase activity.
 
  
 0.894
agaC_4
PTS sorbose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.884
manZ_4
PTS mannose transporter subunit IID; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.876
manZ_5
PTS mannose transporter subunit IID; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.874
AKL33629.1
PTS sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.874
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.