STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lsrRTranscriptional regulator LsrR; Regulates the transcription of lsr genes; involved in autoinducer 2 uptake, biofilm formation and stress responses; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)    
Predicted Functional Partners:
AKL34300.1
Autoinducer kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.903
AKL34304.1
Autoinducer 2-binding protein lsrB; With lsrACD is involved in the transport of autoinducer 2 into the cell; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.891
lsrG
Autoinducer-2 (AI-2) modifying protein LsrG; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5- phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5- phosphonooxypentane-2,4-dione (P-HPD); Belongs to the LsrG family.
 
  
 0.826
lsrF_1
Involved in autoinducer 2 transport and processing; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.791
lsrD_1
With IsrABC is involved with autoinducer 2 import; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.764
rhaS-2
ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.660
lsrC
ABC transporter permease; With LsrADB is involved in the transport of autoindiuce 2; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.612
lsrA
ABC transporter ATP-binding protein; With LsrCDB is involved in the transport of autoindiuce 2; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.554
lsrF_1-2
Phospho-2-dehydro-3-deoxyheptonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.526
AKL34320.1
DhaM; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family.
 
  
 0.467
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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