Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
acoR_1Transcriptional regulator; Positively regulates the dhaKLM operon from a sigma-70 promoter; Derived by automated computational analysis using gene prediction method: Protein Homology. (637 aa)    
Predicted Functional Partners:
dhaL
Dihydroxyacetone kinase; With DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.942
dhaK_1
With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.911
dhaK
Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.889
AKL34320.1
DhaM; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family.
 
   
 0.836
gldA-2
Glycerol dehydrogenase; Forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.800
rpoN
RNA polymerase factor sigma-54; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the nitrogen fixation genes. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein NifA for the expression of the nitrogen fixation proteins.
 
  
 0.783
gldA
Glycerol dehydrogenase; Forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.601
AKL34524.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.514
yqhD_1
Aldehyde reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.505
AKL34326.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.465
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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