STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKL34360.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)    
Predicted Functional Partners:
nudF
ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.862
cpdA_1
Diguanylate phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
  
  
 0.774
AKL34362.1
Esterase; Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.774
rsd
anti-RNA polymerase sigma 70 factor; Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
  
     0.670
AKL35374.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.645
ygdR_1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.636
parE
DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
       0.634
tolC
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.616
yibL
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.597
ygfY
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.590
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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