Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yqhD_1Aldehyde reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)    
Predicted Functional Partners:
gldA
Glycerol dehydrogenase; Forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.949
gldA-2
Glycerol dehydrogenase; Forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.946
mgsA
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
  
 
 0.941
iolS_3
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.912
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
    0.798
dkgA
2,5-diketo-D-gluconic acid reductase; Methylglyoxal reductase/beta-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.673
AKL34377.1
AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.649
adhP
Ethanol-active dehydrogenase/acetaldehyde-active reductase; Similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.520
acoR_1
Transcriptional regulator; Positively regulates the dhaKLM operon from a sigma-70 promoter; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.505
AKL36401.1
NADP-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.470
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.