| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKL34531.1 | dnaG | AB185_11745 | AB185_10655 | ssDNA exonuclease RecJ; 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.597 |
| AKL34531.1 | dsbC | AB185_11745 | AB185_11740 | ssDNA exonuclease RecJ; 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein-disulfide isomerase; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. | 0.807 |
| AKL34531.1 | mfd | AB185_11745 | AB185_24725 | ssDNA exonuclease RecJ; 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.624 |
| AKL34531.1 | mutS | AB185_11745 | AB185_12975 | ssDNA exonuclease RecJ; 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.563 |
| AKL34531.1 | prfB | AB185_11745 | AB185_11750 | ssDNA exonuclease RecJ; 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.583 |
| AKL34531.1 | recG | AB185_11745 | AB185_07855 | ssDNA exonuclease RecJ; 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.570 |
| AKL34531.1 | smf | AB185_11745 | AB185_09555 | ssDNA exonuclease RecJ; 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA processing protein DprA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.647 |
| AKL34531.1 | topA | AB185_11745 | AB185_23795 | ssDNA exonuclease RecJ; 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.601 |
| AKL34531.1 | xerD | AB185_11745 | AB185_11735 | ssDNA exonuclease RecJ; 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Site-specific tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifical [...] | 0.750 |
| AKL34531.1 | xseA | AB185_11745 | AB185_14865 | ssDNA exonuclease RecJ; 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.586 |
| dnaG | AKL34531.1 | AB185_10655 | AB185_11745 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | ssDNA exonuclease RecJ; 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.597 |
| dnaG | recG | AB185_10655 | AB185_07855 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.543 |
| dnaG | topA | AB185_10655 | AB185_23795 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.500 |
| dsbC | AKL34531.1 | AB185_11740 | AB185_11745 | Protein-disulfide isomerase; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. | ssDNA exonuclease RecJ; 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.807 |
| dsbC | prfB | AB185_11740 | AB185_11750 | Protein-disulfide isomerase; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.479 |
| dsbC | xerD | AB185_11740 | AB185_11735 | Protein-disulfide isomerase; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. | Site-specific tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifical [...] | 0.802 |
| mfd | AKL34531.1 | AB185_24725 | AB185_11745 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | ssDNA exonuclease RecJ; 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.624 |
| mfd | mutS | AB185_24725 | AB185_12975 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.575 |
| mfd | prfB | AB185_24725 | AB185_11750 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.661 |
| mfd | recG | AB185_24725 | AB185_07855 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.545 |