tas protein (Klebsiella oxytoca) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

tas

Aldo/keto reductase; Complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)

Predicted Functional Partners:

AKL36073.1

0.699

ygdR_1

0.662

AKL35436.1

0.560

phoP_1

0.560

walR

0.560

ygdQ

0.484

arlR

0.471

AKL36815.1

0.457

dkgA

0.440

dkgB

0.440

Your Current Organism:

Klebsiella oxytoca

NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKL35436.1	AKL36073.1	AB185_16685	AB185_20185	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.477
AKL35436.1	tas	AB185_16685	AB185_12310	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aldo/keto reductase; Complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.560
AKL36073.1	AKL35436.1	AB185_20185	AB185_16685	Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.477
AKL36073.1	phoP_1	AB185_20185	AB185_25505	Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.477
AKL36073.1	tas	AB185_20185	AB185_12310	Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aldo/keto reductase; Complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.699
AKL36073.1	walR	AB185_20185	AB185_26730	Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.477
AKL36815.1	tas	AB185_24225	AB185_12310	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aldo/keto reductase; Complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.457
arlR	tas	AB185_25065	AB185_12310	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aldo/keto reductase; Complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.471
dkgA	tas	AB185_10890	AB185_12310	2,5-diketo-D-gluconic acid reductase; Methylglyoxal reductase/beta-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aldo/keto reductase; Complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.440
dkgB	tas	AB185_30800	AB185_12310	Catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aldo/keto reductase; Complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.440
phoP_1	AKL36073.1	AB185_25505	AB185_20185	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.477
phoP_1	tas	AB185_25505	AB185_12310	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aldo/keto reductase; Complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.560
tas	AKL35436.1	AB185_12310	AB185_16685	Aldo/keto reductase; Complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.560
tas	AKL36073.1	AB185_12310	AB185_20185	Aldo/keto reductase; Complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.699
tas	AKL36815.1	AB185_12310	AB185_24225	Aldo/keto reductase; Complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.457
tas	arlR	AB185_12310	AB185_25065	Aldo/keto reductase; Complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.471
tas	dkgA	AB185_12310	AB185_10890	Aldo/keto reductase; Complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; Derived by automated computational analysis using gene prediction method: Protein Homology.	2,5-diketo-D-gluconic acid reductase; Methylglyoxal reductase/beta-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.440
tas	dkgB	AB185_12310	AB185_30800	Aldo/keto reductase; Complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; Derived by automated computational analysis using gene prediction method: Protein Homology.	Catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.440
tas	phoP_1	AB185_12310	AB185_25505	Aldo/keto reductase; Complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.560
tas	walR	AB185_12310	AB185_26730	Aldo/keto reductase; Complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.560

page 1 of 2

Server load: low (12%) [HD]

Permalink

Network

Neighborhood

Experiments

Co-occurrence

Textmining

Co-expression

Databases

Fusion

© STRING Consortium 2026

Credits

Access

Info

About