| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKL34653.1 | AKL34654.1 | AB185_12400 | AB185_12405 | Threonine-phosphate decarboxylase; Cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GHMP kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.969 |
| AKL34653.1 | AKL34684.1 | AB185_12400 | AB185_12555 | Threonine-phosphate decarboxylase; Cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin biosynthesis protein CbiG; Catalyzes the formation of cobalt-precorrin 4 from cobalt-precorrin 3; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.837 |
| AKL34653.1 | cbiA | AB185_12400 | AB185_12520 | Threonine-phosphate decarboxylase; Cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.982 |
| AKL34653.1 | cbiC | AB185_12400 | AB185_12530 | Threonine-phosphate decarboxylase; Cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | precorrin-8X methylmutase; Catalyzes the interconversion of cobalt-precorrin-8X and cobyrinic acid in the anaerobic biosynthesis of cobalamin; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.912 |
| AKL34653.1 | cbiF | AB185_12400 | AB185_12550 | Threonine-phosphate decarboxylase; Cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of cobalt-precorrin-5 from cobalt-precorrin-4; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.844 |
| AKL34653.1 | cobD | AB185_12400 | AB185_12525 | Threonine-phosphate decarboxylase; Cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.984 |
| AKL34653.1 | cobQ | AB185_12400 | AB185_12600 | Threonine-phosphate decarboxylase; Cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin biosynthesis protein CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.979 |
| AKL34653.1 | hisB | AB185_12400 | AB185_16910 | Threonine-phosphate decarboxylase; Cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Imidazoleglycerol-phosphate dehydratase; Catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the histidinol- phosphatase family. | 0.967 |
| AKL34653.1 | hisD | AB185_12400 | AB185_16920 | Threonine-phosphate decarboxylase; Cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.873 |
| AKL34653.1 | hisI | AB185_12400 | AB185_16890 | Threonine-phosphate decarboxylase; Cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | phosphoribosyl-ATP pyrophosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | 0.975 |
| AKL34654.1 | AKL34653.1 | AB185_12405 | AB185_12400 | GHMP kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine-phosphate decarboxylase; Cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.969 |
| AKL34654.1 | AKL34684.1 | AB185_12405 | AB185_12555 | GHMP kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin biosynthesis protein CbiG; Catalyzes the formation of cobalt-precorrin 4 from cobalt-precorrin 3; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.901 |
| AKL34654.1 | cbiA | AB185_12405 | AB185_12520 | GHMP kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.533 |
| AKL34654.1 | cbiC | AB185_12405 | AB185_12530 | GHMP kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | precorrin-8X methylmutase; Catalyzes the interconversion of cobalt-precorrin-8X and cobyrinic acid in the anaerobic biosynthesis of cobalamin; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.634 |
| AKL34654.1 | cbiF | AB185_12405 | AB185_12550 | GHMP kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of cobalt-precorrin-5 from cobalt-precorrin-4; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.546 |
| AKL34654.1 | cobD | AB185_12405 | AB185_12525 | GHMP kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.473 |
| AKL34654.1 | cobQ | AB185_12405 | AB185_12600 | GHMP kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin biosynthesis protein CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.569 |
| AKL34684.1 | AKL34653.1 | AB185_12555 | AB185_12400 | Cobalamin biosynthesis protein CbiG; Catalyzes the formation of cobalt-precorrin 4 from cobalt-precorrin 3; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine-phosphate decarboxylase; Cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.837 |
| AKL34684.1 | AKL34654.1 | AB185_12555 | AB185_12405 | Cobalamin biosynthesis protein CbiG; Catalyzes the formation of cobalt-precorrin 4 from cobalt-precorrin 3; Derived by automated computational analysis using gene prediction method: Protein Homology. | GHMP kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.901 |
| AKL34684.1 | cbiA | AB185_12555 | AB185_12520 | Cobalamin biosynthesis protein CbiG; Catalyzes the formation of cobalt-precorrin 4 from cobalt-precorrin 3; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.977 |