| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKL34805.1 | AKL34807.1 | AB185_13225 | AB185_13235 | Hydrogenase isoenzymes formation protein HypD; Necessary for the synthesis of all three hydrogenase isoenzymes; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HypD family. | Hydrogenase nickel incorporation protein HypB; GTP hydrolase involved in nickel liganding into hydrogenases; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.984 |
| AKL34805.1 | AKL34822.1 | AB185_13225 | AB185_13310 | Hydrogenase isoenzymes formation protein HypD; Necessary for the synthesis of all three hydrogenase isoenzymes; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HypD family. | Carbamoyl phosphate phosphatase; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | 0.901 |
| AKL34805.1 | hycE | AB185_13225 | AB185_13265 | Hydrogenase isoenzymes formation protein HypD; Necessary for the synthesis of all three hydrogenase isoenzymes; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HypD family. | Hydrogenase 3 large subunit; Formate hydrogenlyase subunit 5; HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.764 |
| AKL34805.1 | hycG | AB185_13225 | AB185_13275 | Hydrogenase isoenzymes formation protein HypD; Necessary for the synthesis of all three hydrogenase isoenzymes; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HypD family. | Formate hydrogenlyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.633 |
| AKL34805.1 | hycI | AB185_13225 | AB185_13285 | Hydrogenase isoenzymes formation protein HypD; Necessary for the synthesis of all three hydrogenase isoenzymes; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HypD family. | Hydrogenase 3 maturation protease; Involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.641 |
| AKL34805.1 | hypA | AB185_13225 | AB185_13240 | Hydrogenase isoenzymes formation protein HypD; Necessary for the synthesis of all three hydrogenase isoenzymes; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HypD family. | Hydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.973 |
| AKL34805.1 | hypC | AB185_13225 | AB185_13230 | Hydrogenase isoenzymes formation protein HypD; Necessary for the synthesis of all three hydrogenase isoenzymes; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HypD family. | Hydrogenase assembly chaperone; HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.998 |
| AKL34805.1 | hypE | AB185_13225 | AB185_13220 | Hydrogenase isoenzymes formation protein HypD; Necessary for the synthesis of all three hydrogenase isoenzymes; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HypD family. | Carbamoyl dehydratase HypE; Hydrogenase isoenzymes formation protein; involved in the formation of the cyanate group of the large subunit of the hydrogenase; catalyzes the formation of thiocyanate from thiocarbamate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.998 |
| AKL34805.1 | ureG | AB185_13225 | AB185_10675 | Hydrogenase isoenzymes formation protein HypD; Necessary for the synthesis of all three hydrogenase isoenzymes; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HypD family. | Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.700 |
| AKL34807.1 | AKL34805.1 | AB185_13235 | AB185_13225 | Hydrogenase nickel incorporation protein HypB; GTP hydrolase involved in nickel liganding into hydrogenases; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase isoenzymes formation protein HypD; Necessary for the synthesis of all three hydrogenase isoenzymes; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HypD family. | 0.984 |
| AKL34807.1 | AKL34822.1 | AB185_13235 | AB185_13310 | Hydrogenase nickel incorporation protein HypB; GTP hydrolase involved in nickel liganding into hydrogenases; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carbamoyl phosphate phosphatase; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | 0.829 |
| AKL34807.1 | hycE | AB185_13235 | AB185_13265 | Hydrogenase nickel incorporation protein HypB; GTP hydrolase involved in nickel liganding into hydrogenases; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase 3 large subunit; Formate hydrogenlyase subunit 5; HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.974 |
| AKL34807.1 | hycG | AB185_13235 | AB185_13275 | Hydrogenase nickel incorporation protein HypB; GTP hydrolase involved in nickel liganding into hydrogenases; Derived by automated computational analysis using gene prediction method: Protein Homology. | Formate hydrogenlyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.498 |
| AKL34807.1 | hycI | AB185_13235 | AB185_13285 | Hydrogenase nickel incorporation protein HypB; GTP hydrolase involved in nickel liganding into hydrogenases; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase 3 maturation protease; Involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.571 |
| AKL34807.1 | hypA | AB185_13235 | AB185_13240 | Hydrogenase nickel incorporation protein HypB; GTP hydrolase involved in nickel liganding into hydrogenases; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.992 |
| AKL34807.1 | hypC | AB185_13235 | AB185_13230 | Hydrogenase nickel incorporation protein HypB; GTP hydrolase involved in nickel liganding into hydrogenases; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrogenase assembly chaperone; HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.988 |
| AKL34807.1 | hypE | AB185_13235 | AB185_13220 | Hydrogenase nickel incorporation protein HypB; GTP hydrolase involved in nickel liganding into hydrogenases; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carbamoyl dehydratase HypE; Hydrogenase isoenzymes formation protein; involved in the formation of the cyanate group of the large subunit of the hydrogenase; catalyzes the formation of thiocyanate from thiocarbamate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.965 |
| AKL34807.1 | slyD | AB185_13235 | AB185_09305 | Hydrogenase nickel incorporation protein HypB; GTP hydrolase involved in nickel liganding into hydrogenases; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidylprolyl isomerase; Rotamase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.629 |
| AKL34822.1 | AKL34805.1 | AB185_13310 | AB185_13225 | Carbamoyl phosphate phosphatase; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | Hydrogenase isoenzymes formation protein HypD; Necessary for the synthesis of all three hydrogenase isoenzymes; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HypD family. | 0.901 |
| AKL34822.1 | AKL34807.1 | AB185_13310 | AB185_13235 | Carbamoyl phosphate phosphatase; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | Hydrogenase nickel incorporation protein HypB; GTP hydrolase involved in nickel liganding into hydrogenases; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.829 |