Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ascG_4Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)    
Predicted Functional Partners:
bglF_1
PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.550
gltB
Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.540
AKL34822.1
Carbamoyl phosphate phosphatase; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
       0.511
hoxN
Nickel transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NiCoT transporter (TC 2.A.52) family.
       0.501
AKL34821.1
Formate dehydrogenase; Involved in electron transport from formate to hydrogen; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.488
bglH_1
6-phospho-beta-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 1 family.
     
 0.468
AKL37011.1
PTS fructose transporter subunit IIA; Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein HPr; HPr transfers the phosphoryl group to subunit A; subunit IIA transfers a phosphoryl group to subunit IIB; subunit IIB transfers the phosphoryl group to the substrate; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.451
AKL34320.1
DhaM; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family.
   
 
 0.428
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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