Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yibH_4With ErmA and TolC forms a multidrug efflux system; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)    
Predicted Functional Partners:
emrB
Multidrug resistance protein B; Multidrug MFS transporte; with EmrA is involved in resistance to hydrophobic antibiotics such as nalidixic acid; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the major facilitator superfamily.
 
 
 0.993
tolC
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.825
mdtD_1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.787
AKL35372.1
Multidrug resistance outer membrane protein MdtQ; May be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.773
AKL34753.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.748
yusO
DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.744
AKL34572.1
Transporter; Part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.743
oprM_2
Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.734
AKL33423.1
RND transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.716
oprM_2-2
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.709
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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