| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKL34531.1 | mutL | AB185_11745 | AB185_33735 | ssDNA exonuclease RecJ; 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.644 |
| AKL34531.1 | recN | AB185_11745 | AB185_14215 | ssDNA exonuclease RecJ; 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Recombination and repair protein; May be involved in recombinational repair of damaged DNA. | 0.638 |
| AKL34531.1 | ruvA | AB185_11745 | AB185_17940 | ssDNA exonuclease RecJ; 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.532 |
| AKL34531.1 | ruvB | AB185_11745 | AB185_17945 | ssDNA exonuclease RecJ; 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.558 |
| AKL34531.1 | uvrB | AB185_11745 | AB185_27200 | ssDNA exonuclease RecJ; 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.421 |
| AKL34531.1 | xseA | AB185_11745 | AB185_14865 | ssDNA exonuclease RecJ; 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.691 |
| AKL34531.1 | xseB | AB185_11745 | AB185_29660 | ssDNA exonuclease RecJ; 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.593 |
| guaA | guaB | AB185_14875 | AB185_14870 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
| guaA | mutL | AB185_14875 | AB185_33735 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.718 |
| guaA | ruvB | AB185_14875 | AB185_17945 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.541 |
| guaA | uvrB | AB185_14875 | AB185_27200 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.544 |
| guaA | xseA | AB185_14875 | AB185_14865 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.648 |
| guaB | guaA | AB185_14870 | AB185_14875 | Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.999 |
| guaB | xseA | AB185_14870 | AB185_14865 | Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.620 |
| ispA | mutL | AB185_29665 | AB185_33735 | Geranyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.573 |
| ispA | xseA | AB185_29665 | AB185_14865 | Geranyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.688 |
| ispA | xseB | AB185_29665 | AB185_29660 | Geranyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.938 |
| mutL | AKL34531.1 | AB185_33735 | AB185_11745 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | ssDNA exonuclease RecJ; 5'-3' single-stranded-DNA-specific exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.644 |
| mutL | guaA | AB185_33735 | AB185_14875 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.718 |
| mutL | ispA | AB185_33735 | AB185_29665 | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Geranyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. | 0.573 |